A comparative study of serum lipid profile and glucose level between breast cancer patients and controls at tertiary care hospital in India

Abstract

Aim

The aim of this study is to compare serum lipid profiles: Total cholesterol, triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol, and serum glucose between breast cancer patients and control to evaluate their relationship with breast cancer.

Background

There are many researches which have reported positive as well as a negative association of plasma/serum lipids and lipoproteins and serum glucose with different cancers. Increase levels of circulating lipids and serum glucose have been associated with breast cancer risk.

Materials and Methods

A total of 92 consecutive cases of histologically proven carcinoma breast along with same number of age-matched, disease-free controls were selected. Serum lipid and serum glucose levels of both cases and controls were estimated.

Results

The results of this study suggest that low (HDL-C) level and high (TG) levels are associated with risk of breast cancer in Indian women while serum glucose level does not show any association with breast cancer risk.

Conclusion: More studies are needed in the future to explore common modifiable risk factors for the development of breast cancer, so that its incidence can be reduced.