Relationship Between Physical Fitness and C-Reactive Protein Level in Adolescent Age (10-18 years) in Bundelkhand Region

Om Shankar Chaurasiya, Ashish Pratap Singh



C-reactive protein (CRP), an acute-phase reactant, is produced in the liver and belongs to the pentraxin family of proteins. Recent data implicate systemic inflammatory factors, including fibrinogen, CRP, and interleukin 6, as important factors for atherosclerosis and cardio vascular disease events. CRP is significantly related to various cardiovascular disease risk factors in children and has been shown to be inversely related to antioxidant concentrations. The presence of early stage atherosclerosis has been documented extensively in children and young adults, but data regarding inflammatory factor in children and adolescents are not so well documented as in adults.

Aims and Objectives:

 To study the relationship between physical fitness and CRP level in the adolescent age group.


The study was conducted from July 2008 to December 2009. Measurement of physical work capacity (PWC) was done by treadmill test according to modified Bruce protocol. We have measured weight, height, resting heart rate, body mass index (BMI), waist-hip ratio (WHR). Measurement of serum CRP level was done by latex agglutination method.


In girls mean CRP levels were higher (0.48 mg/L) as compared to boys (0.42 mg/L). In girls mean BMI were higher (19.46%) than boys (18.17%). In girls mean WHR were higher (0.85) than boys (0.84%). In girls mean PWC (3.81) was lower than boys (4.13). CRP level tended to be higher in higher weight children (means of 0.35, 0.40, 0.45, 0.55 for children < 30, 31-40, 41-50 and > 50 kg respectively).


We had seen the significant positive correlation of CRP with BMI, weight and height and significant negative correlation with PWC.


Body mass index, C-reactive protein, physical fitness

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