Minimal change disease

Sanjeev Narang

Abstract


Minimal change disease or nephrosis lipoid
On light microscopy, of changes devoid.
• 80% of nephrotics, it does comprise
Boys below 16 years pay the price.
• Idiopathic it is, cause unknown
Possible mechanisms immune have been shown.
• In the net of protein loss, albumin is caught
Label of selective proteinuria, it has got.
• No change grossly it does produce
Shape and size, increase nor reduce.
• Changes in glomeruli and tubules are slight
Noted this is on microscopy light.
• On EM, flat, foot processes of podocytes seen
Labeled as the foot process disease it has been.
• Immunofluorescence - absent deposits does claim
Hence, “nil deposit disease” is also its name.


Keywords


Minimal Change Disease, Kidney, Nephrotic Disease.

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Copyright © 2014 International Journal of Medical Science Research and Practice. All rights reserved. Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.